Terramycin as a Therapeutic Agent against Mumps

Clinical Observations on Terramycin *†

In a recent report, Finlay, Hobby, and their collaborators1 have described a new crystalline antibiotic, terramycin, isolated from broth cultures of a new actinomycete, Streptomnyces rimosus. In vitro studies8 of terramycin and its salts have shown that this antibiotic in low concentrations is a highly effective bacteriostatic agent against a wide variety of gram-positive and gram-negative bact...

Recombinant mumps virus as a cancer therapeutic agent

Mumps virus belongs to the family of Paramyxoviridae and has the potential to be an oncolytic agent. Mumps virus Urabe strain had been tested in the clinical setting as a treatment for human cancer four decades ago in Japan. These clinical studies demonstrated that mumps virus could be a promising cancer therapeutic agent that showed significant antitumor activity against various types of cance...

Chemotherapy of virus infections.

In recent years, antibiotics have proved effective against many bacterial and all rickettsial infections of man, but are only of limited value in virus infections. The so-called broad spectrum antibiotics-aureomycin, terramycin and chloramphenicol-are effective against the viruses of the psittacosis-lymphogranuloma group and those causing primary atypical pneumonia. Many substances are therefor...

The Protection of Intracellular Brucella against Therapeutic Agents and the Bactericidal Action of Serum

A method for the in vitro study of intracellular brucella has been described. Exudative leukocytes containing intracellular brucella have been maintained in vitro in a synthetic tissue culture medium or in human or animal serum. Intracellular brucella are protected in vitro against the lethal action of therapeutic agents or the bactericidal action of serum. This protection of intracellular bruc...

The Therapeutic Value of Oxyteracycline Hydrochloride (Terramycin) in Cattle Infected Experimentally with Theileria annulata